Where to Farm for Runes, Uniques, Set and more in Diablo 2 Resurrected

In Diablo 2 Resurrected, efficient farming locations can significantly enhance your chances of acquiring valuable items, runes, and uniques.

Worldstone Keep & Baal:
Worldstone Keep is an Area Level (alvl) 85 zone where elite packs can drop every set and unique item in the game. Farming here is incredibly valuable.
Baal, the final boss, also drops high-level loot. Clearing the Worldstone Keep and defeating Baal can yield excellent rewards.

Chaos Sanctuary:
The Chaos Sanctuary is arguably the best overall area to farm. It features Diablo (The Lord of Terror) himself and several bosses.
You’ll find unique and set items, runes, and bases here. While Nightmare difficulty has its purposes, Hell difficulty is the primary focus for farming.

The Mausoleum, The Pit, The Secret Cow Level (Act 1):
These areas in Act 1 (Hell difficulty) are excellent for farming. The Mausoleum, The Pit (levels 1 and 2), and the whimsical Secret Cow Level offer valuable loot and rune drops.

Travincal (Act 3):
Travincal is another lucrative spot. Farm it for runes, uniques, and set items. Adjust the player count to optimize your drops.